Swiftly playing the ball back in side, former Liverpool man Philippe Coutinho was on-hand to finish the chance off well.
Messi earned the plaudits with a brace as LaLiga holders Barcelona overcame a depleted Tottenham side 4-2 at Wembley in London on Wednesday.
That's a pretty simple lesson and one that many teams have learned in the past, so it's very surprising that Spurs boss Mauricio Pochettino allowed his players to grant so much green grass - well, actually brown dust considering the shocking state of the Wembley "turf" - to the visitors.
Barcelona ran out 4-2 winners in the end at Wembley but Spurs almost forced a famous comeback after clawing the game back to 3-2.
In their Group B opener last month, Spurs suffered a 2-1 loss to Inter Milan.
Considering his well-earned reputation as one of the world's most feared strikers, it is nearly inexplicable that Luis Suarez has now gone more than three years without an away goal in the Champions League.
The little genius was inches away from putting the game to bed two minutes into the second half as he hit the base of the left post with a guided shot from the edge of the box, and Messi was denied by the woodwork again on 51 minutes with a carbon copy of his previous effort.
After Tottenham striker Harry Kane pulled one back in the 52nd minute, Messi started and completed the move four minutes later that restored Barcelona's two-goal lead.
"Our players were heroes because they were chasing the game against Messi, Suarez, Coutinho and Co".
"We had a few problems", Barcelona coach Ernesto Valverde said.
If you give plenty of space to Barcelona to play in midfield, you will die. If Lucas Moura scored the third goal sure we talk about we are heroes and the manager is the best in the world.
But question marks do remain about their ability to seriously challenge for the Champions League title this season, despite making it two wins from two to open up group play.
"It's never easy to be an away team in the Champions League and even less so against a team like Tottenham". It will be tough because they are must-win games. "We're still thinking the same, though, that all is possible".