At Hamburg - who had survived the relegation play-offs in 2014 and 2015, then narrowly escaped to safety on the final day of the Bundesliga season past year - Gladbach fans mocked their counterparts by unfurling their own clock which ticked down towards their opponents' impending demotion, and as the game entered stoppage time a number of home fans hurled flares towards the pitch.
Hamburg had battled to victory over Moenchengladbach, but were doomed to relegation as Wolfsburg beat Cologne 4-1.
Hamburg have been relegated from the Bundesliga for the first time despite a 2-1 win over Borussia Monchengladbach.
Dozens of riot police, several on horses, charged on to the pitch and lined up in front of the Hamburg fans, who lit flares and threw them behind the Gladbach goal when it became clear that the team was on their way to the second division.
Some Hamburg players broke down and cried after referee Felix Brych finally ended the game after a long hold up due to the disturbances.
As the only club to have played in every Bundesliga season since its inception in 1963, supporters of the six-time German champions have proudly displayed a clock at Volksparkstadion which keeps a record of their top-flight status. Titz reinvigorated the side over his eight games in charge.
Elsewhere, Hoffenheim and Borussia Dortmund joined Schalke and champions Bayern Munich in the league's top four.
Dortmund's marginally better goal difference - three goals - over Bayer Leverkusen, who conceded two goals against Hanover after leading 3-0, meant they finished fourth and grabbed the lucrative European spot which takes them into the group stage.
Everton loanee Ademola Lookman ran the show with a goal and two assists as RB Leipzig booked Europa League football by winning 6-2 at Hertha Berlin.
Bayern, though, were unable to give coach Jupp Heynckes an appropriate send-off in his final home game, as they stumbled to a shock 4-1 defeat to Stuttgart.