Cosby is charged with three counts of aggravated indecent assault - all stemming from Andrea Constand's allegations that he knocked her out with three pills he called "your friends" and molested her at his suburban Philadelphia mansion in January 2004.
Cosby faces up to 10 years in prison for each count. He is likely to get less than that under state sentencing guidelines, but given his age, even a modest term could mean he will die behind bars.
The first ended in a mistrial previous year when jurors couldn't reach a verdict, but the second comes on the heels of the #MeToo movement that has raised awareness on predatory practices by power players in Hollywood and other industries. He also said the sexual encounter was consensual. Constand was also pressed about the almost $3.4 million Cosby paid her in a 2006 civil settlement, which was previously confidential.
Another prosecutor, Kristen Feden, said Cosby was "nothing like the image that he played on TV" as sweater-wearing, wisdom-dispensing father of five Dr. Cliff Huxtable on "The Cosby Show". Last year, just one other accuser could take the stand. Cosby's lawyers had motioned to prevent the other accusers from testifying, fearing a #MeToo atmosphere would take over the courtroom.
The jury, which had to come to a unanimous decision to convict or acquit, saw a parade of accusers testify that the man once revered as "America's Dad" had a secret life of drugging and violating women. Judge Steven O'Neill informed the jurors that after the exhaustive trial, they would be provided with a comfort dog before they returned to their hotel, the New York Daily News reports. But the defense team made an unsubtle attack on it when lawyer Kathleen Bliss told the panel that "when you join a movement based mostly on emotion and anger, you don't change a damn thing", adding that "mob rule is not due process". "The women who have come forward are strong and courageous, and they have delivered hope to the countless women whose abusers have yet to be held accountable".
Cosby is accused of drugging and molesting Constand in 2004.
Exhausted jurors called it a night after rehearing excerpts from Cosby's old deposition testimony.
Cosby had been a transcendent figure in show business, coming up as a black comedian during the civil rights movement of the 1960s and winning over white audiences with a clean routine.
Later in his career, he attracted controversy for lecturing about social dysfunction in poor black neighborhoods, railing against young people stealing things and wearing baggy trousers.
Its release in 2015 set Cosby's downfall in motion, prompting authorities to reopen the criminal investigation and bring charges.
Constand initially told police about the assault in 2005, a year after the assault occurred.