The Yankees were built to feast on left-handed pitching this season, but they struggled against the best southpaw in the American League. But it took until his third time through the lineup to get anything going off Red Sox starter Chris Sale, when he squeaked a base hit into center field in the sixth inning.
Sale also overmatched Gary Sanchez, inducing a groundout and a pop-up - and striking him out swinging with a nasty slider that broke across the plate and landed behind the Yankee catcher.
Yankees slugger Giancarlo Stanton went 2 for 4.
Severino had been crafting a bit of a reputation as an outstanding road pitcher before Tuesday night's outing. The 116.3-mph blast was the hardest home run ever hit off the Red Sox ace. Much has been talked about at the start of the season regarding which team will potentially win the division [VIDEO] vs. a wild card spot. Betts went 4 for 4, scoring five runs and driving in four.
Betts battled a sore wrist through most of past year, but he's completely healthy and locked in to start the season.
Through the first 10 games Harper leads the league in home runs and is comfortably ahead of the field in drawing walks; incredibly he has hit a home run more often than he has been struck out, highlighting himself as the biggest threat to pitchers in the majors. But the reality is the Yankees got steamrolled in their first matchup against the Red Sox, and Stanton did little to help out on the scoreboard.
Washington Nationals' Stephen Strasburg tossed eight innings of three-hit, shut-out ball in a 4-1 win over the Atlanta Braves.
After giving up a run in the first inning when he needed 22 pitches to record three outs and leave the bases loaded, Severino gave up a leadoff single to Christian Vazquez and a one-out single to Betts in the second. Some say the Red Sox were the favorite, but many picked the Yankees. The RBI was Ramirez's second extra-inning, game-winning hit in as many games.
"I don't know if I was tipping or they saw something, but the game is not the time to work on that", Severino said postgame, according to Bryan Hoch of MLB.com.
"I'm going to be honest with you", he told reporters.
Cardinals 5, Brewers 3 (11 innings): Matt Carpenter cracked a two-run homer in the bottom of the 11th inning as St. Louis outlasted visiting Milwaukee. He entered Tuesday's game 4-for-39 (.103) with 21 strikeouts and one home run over the nine games since Opening Day.
On Tuesday, Betts opened his hitting with a double in the first and scored on a single by Hanley Ramirez. His sixth inning grand slam was the first by a hitter for the Red Sox against NY since September of 2013.
Yankees relievers have allowed 53 runs (45 earned) over 96 innings this season.