In a statement on Thursday that seemed aimed at providing a note of stability, the company said that Mr. Parker would remain in his role at Nike past 2020.
Nike is due to report earnings next week.
Parker said Nike would be reviewing the company's protocol for dealing with internal complaints, the Journal reported. Following Edwards resignation, Nike will "allow for closer management and a sharper focus on our culture", the memo disclosed.
A spokeswoman for Nike confirmed there had been, "conduct inconsistent with Nike's core values and against our code of conduct", but added that there was no direct allegations of misconduct against Edwards.
Nike's brand president and no. 2 executive Trevor Edwards has resigned from the company amid an investigation of inappropriate workplace behavior, The Wall Street Journal reported Thursday.
Nike is in the process of transitioning its business and will use Edwards as a consultant until August, when he will officially retire. "Trevor has chose to retire", said Parker commenting on the development.
"I'd like to thank Trevor for the important role he has played for 25 years and for his significant contributions".
The shake-up comes as Nike tries to cope with a sales slump in its key North American market.
An internal memo detailing the claims, written by Nike Chief Executive Officer Mark Parker, has since been circulating in full on social media. He joined the company in 1992 as a regional marketing manager.
Meanwhile, Parker will stay on as CEO beyond 2020 - when he will turn 65. "We are fortunate to have a strong management team in place who is well suited to drive our next stage of growth and to steward and evolve our culture in the future".