The visitors outplayed Liverpool after the break and found an equaliser through a stunning Victor Wanyama strike ten minutes from time. Then Spurs won a penalty, which Harry Kane surprisingly missed. He had only come on as a substitute a minute earlier.
Van Dijk was largely imperious on his return- in the first half at least - preventing Kane from having a single touch inside Liverpool's penalty area before the break.
The fast and nervy start led to plenty of open play, but few real chances. Young Trent Alexander-Arnold will be on their right and Andrew Robertson will be on their right.
Liverpool FC haven't won the Premier League title but finished in second place in 2002, 2009 and 2014.
Talking in his column in the Evening Standard, Murphy said: "Harry Kane was able to dominate United's Phil Jones and Chris Smalling and he will hope to do the same against Virgil van Dijk and Joel Matip".
Team-mate Alli stole the headlines for all the wrong reasons with 20 minutes left on the clock, as he was booked for simulation after an terrible dive.
Spurs finally worked Karius five minutes before the break, a rifled Mousa Dembele 20-yard drive forcing a decent save down to the goalkeeper's right. The stopper redeemed himself, however, saving the penalty. Pochettino said Kane had "big balls" to score so many EPL goals and to have taken the second penalty soon after missing the first.
Salah was briefly level with Kane on 21 goals for the season, only for the Tottenham striker to move back in front after Virgil van Dijk was adjudged to have kicked Erik Lamela.
Now look: you can make an argument that it's unfair that this incident, which was moderately off the ball, resulted in a penalty that is 85% likely to end with a goal.
"It was clear, two sides high quality who wanted to win desperate, obviously". Did you ever hear [referees explain themselves]? "I am not allowed to go in their room until half an hour after", Klopp told Sky Sports.
Salah will also be in Russian Federation with Egypt and the continuation of this form by both men for club and country could see Real Madrid attempt to make one of them football's first £200 million player.
A situation in the last minute like that? Wow. "In the end I think it was a fantastic game and a little bit lucky for them that they got one point". However, we are going for a 2-2 draw as our prediction at the best odds of 12/1 at the same bookmaker.
Van Dijk was also unhappy with the award of the second penalty when Lamela went down as the Dutchman tried to clear the ball. "Sometimes you complain but, when they are right and show character, I think it is important to recognise and congratulate them, because they have a hard job".
The Reds' next outing will be against Southampton, while Spurs host Newport in a cup replay.